BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis.
- Assistant Professor
- Bioinformatics and Computational Biology
- Biology
- Cell and Developmental Biology
- Ecology and Evolutionary Biology
- Genetics and Genomics
311 Thomas Hunt Morgan
(859) 257-0124
| Title | BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis. |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Journal | Gut |
| Volume | 66 |
| Issue | 5 |
| Pagination | 852-862 |
| ISSN | 0017-5749 |
| Abstract | Blood vessel epicardial substance (BVES) is a tight junction-associated protein that regulates epithelial-mesenchymal states and is underexpressed in epithelial malignancy. However, the functional impact of BVES loss on tumourigenesis is unknown. Here we define the in vivo role of BVES in colitis-associated cancer (CAC), its cellular function and its relevance to patients with IBD. |
| URL | http://gut.bmj.com/cgi/pmidlookup?view=long&pmid=28389570 |
| DOI | 10.1136/gutjnl-2015-310255 |
| Short Title | Gut |
