Chickens' Cry2: molecular analysis of an avian cryptochrome in retinal and pineal photoreceptors.

TitleChickens' Cry2: molecular analysis of an avian cryptochrome in retinal and pineal photoreceptors.
Publication TypeJournal Article
Year of Publication2002
JournalFEBS letters
Volume513
Issue2-3
Pagination169-74
Date Published2002
ISSN0014-5793
Abstract

We have identified and characterized an ortholog of the putative mammalian clock gene cryptochrome 2 (Cry2) in the chicken, Gallus domesticus. Northern blot analysis of gCry2 mRNA indicates widespread distribution in central nervous and peripheral tissues, with very high expression in pineal and retina. In situ hybridization of chick brain and retina reveals expression in photoreceptors and in visual and circadian system structures. Expression is rhythmic; mRNA levels predominate in late subjective night. The present data suggests that gCry2 is a candidate avian clock gene and/or photopigment and set the stage for functional studies of gCry2.

URLhttp://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0014-5793&date=2002&volume=513&issue=2-3&spage=169
Short TitleFEBS Lett
X
Enter your linkblue username.
Enter your linkblue password.
Secure Login

This login is SSL protected

Loading