Efficacy and safety of flavocoxid compared with naproxen in subjects with osteoarthritis of the knee- a subset analysis.

TitleEfficacy and safety of flavocoxid compared with naproxen in subjects with osteoarthritis of the knee- a subset analysis.
Publication TypeJournal Article
Year of Publication2010
JournalAdvances in therapy
Volume27
Issue12
Pagination953-62
ISSN0741-238X
Abstract

twice-daily flavocoxid, a cyclooxygenase and 5-lipoxygenase inhibitor with potent antioxidant activity of botanical origin, was evaluated for 12 weeks in a randomized, double-blind, active-comparator study against naproxen in 220 subjects with moderate-severe osteoarthritis (OA) of the knee. As previously reported, both groups noted a significant reduction in the signs and symptoms of OA with no detectable differences in efficacy between the groups when the entire intent-to-treat population was considered. This post-hoc analysis compares the efficacy of flavocoxid to naproxen in different subsets of patients, specifically those related to age, gender, and disease severity as reported at baseline for individual response parameters.

URLhttp://dx.doi.org/10.1007/s12325-010-0083-9
DOI10.1007/s12325-010-0083-9
Short TitleAdv Ther
X
Enter your linkblue username.
Enter your linkblue password.
Secure Login

This login is SSL protected

Loading