Genetic mapping of the Mx influenza virus resistance gene within the region of mouse chromosome 16 that is homologous to human chromosome 21.

TitleGenetic mapping of the Mx influenza virus resistance gene within the region of mouse chromosome 16 that is homologous to human chromosome 21.
Publication TypeJournal Article
Year of Publication1988
JournalJournal of virology
Volume62
Issue11
Pagination4372-5
ISSN0022-538X
Abstract

A total of 318 progeny from four backcrosses involving different laboratory strains and subspecies of Mus musculus were analyzed to map the Mx gene to the region of mouse chromosome 16 (MMU 16) which is homologous to human chromosome 21 (HSA 21). This result suggests that Mx will be found in the region of HSA 21 which has been implicated in Down syndrome when inherited in three copies.

URLhttp://jvi.asm.org/cgi/pmidlookup?view=long&pmid=2902234
Short TitleJ Virol
X
Enter your linkblue username.
Enter your linkblue password.
Secure Login

This login is SSL protected

Loading