Rod progenitor cells in the mature zebrafish retina.

TitleRod progenitor cells in the mature zebrafish retina.
Publication TypeJournal Article
JournalAdvances in experimental medicine and biology
Volume613
Pagination361-8
Date Published2008
ISSN0065-2598
Abstract

The zebrafish is an excellent model organism in which to study the retina's response to photoreceptor degeneration and/or acute injury. While much has been learned about the retinal stem and progenitor cells that mediate the damage response, several questions remain that cannot be addressed by acute models of injury. The development of genetic models, such as the XOPS-mCFP transgenic line, should further efforts to understand the nature of the signals that promote rod progenitor proliferation and differentiation following photoreceptor loss. This in turn may help to refine future approaches in higher vertebrates aimed at enhancing retinal progenitor cell activity for therapeutic purposes.

URLhttps://dx.doi.org/10.1007/978-0-387-74904-4_42
DOI10.1007/978-0-387-74904-4_42
Short TitleAdv Exp Med Biol
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