Sympathetic regulation of chicken pineal rhythms.

TitleSympathetic regulation of chicken pineal rhythms.
Publication TypeJournal Article
Year of Publication1983
JournalBrain research
Volume272
Issue2
Pagination311-7
Date Published1983
ISSN0006-8993
Abstract

Adult hens were chronically cannulated and held in light-dark (LD) 12:12 h lighting regimes or in constant darknesS (DD). Periodic blood sampling for 5-9 days revealed circadian rhythms in plasma melatonin titres. Superior cervical ganglionectomy (SCG-X) performed 1 week after hatching had little or no effect on these rhythms in LD, but unlike normals. SCG-X birds did not sustain persistent rhythms in DD. In SCG-X birds, norepinephrine (NE) infusion for 12 h of each 24 h in DD significantly reduced plasma melatonin titres during the infusion and re-established a rhythm. After each experiment, hens were killed, their pineals were removed and assayed by HPLC-EC for NE, dopamine (DA), serotonin (5-HT) and 5-hydroxy-3-indole-acetic acid (5-HIAA). SCG-X resulted in a 90% depletion of pineal NE: DA content was reduced to undetectable levels. Pineal 5-HT and 5-HIAA were also reduced by SCG-X. The chicken pineal contains circadian oscillators which persist in vitro8.19.29. The results reported here suggest that noradrenergic fibres from the SCG regulate the pineal's inherent rhythmicity. NE normally released from sympathetic terminals during the bird's day may synchronize oscillators within the pineal by inhibiting melatonin synthesis.

URLhttps://linkinghub.elsevier.com/retrieve/pii/0006-8993(83)90578-4
Short TitleBrain Res
X
Enter your linkblue username.
Enter your linkblue password.
Secure Login

This login is SSL protected

Loading