Elevated plasma catecholamines functionally compensate for the reduced myogenic tone in smooth muscle STIM1 knockout mice but with deleterious cardiac effects.
| Author | |
|---|---|
| Abstract | :
Stromal interaction molecule 1 (STIM1) has emerged as an important player in the regulation of growth and proliferation of smooth muscle cells. Therefore, we hypothesized that STIM1 plays a crucial role in the maintenance of vascular integrity. The objective of this study was to evaluate whether reduced expression of STIM1 could modify the structure and function of the vasculature, leading to changes in blood pressure (BP). |
| Year of Publication | :
2018
|
| Journal | :
Cardiovascular research
|
| Date Published | :
2018
|
| ISSN Number | :
0008-6363
|
| URL | :
https://academic.oup.com/cardiovascres/article-lookup/doi/10.1093/cvr/cvy015
|
| DOI | :
10.1093/cvr/cvy015
|
| Short Title | :
Cardiovasc Res
|
| Download citation |