Impact of Multigene Panel Testing on Surgical Decision Making in Breast Cancer Patients.
Author | |
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Abstract | :
With the advent of multi-gene panel testing for breast cancer patients, germline mutations with unknown association with cancer risk, known as variants of uncertain significance (VUS), are being increasingly identified. Some studies have shown higher rates of contralateral prophylactic mastectomies (CPM) in these patients despite lack of evidence to support this intervention. We analyzed surgical choices in patients who were identified to have VUS. |
Year of Publication | :
2018
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Journal | :
Journal of the American College of Surgeons
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Date Published | :
2018
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ISSN Number | :
1072-7515
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URL | :
http://linkinghub.elsevier.com/retrieve/pii/S1072-7515(18)30018-8
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DOI | :
10.1016/j.jamcollsurg.2017.12.037
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Short Title | :
J Am Coll Surg
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