Impact of Drug-Polymer Miscibility on Enthalpy Relaxation of Irbesartan Amorphous Solid Dispersions.
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Abstract | :
Drug-polymer miscibility has been proposed to play a critical role in physical stability of amorphous solid dispersions (ASDs). The purpose of the current work was to investigate the role of drug-polymer miscibility on molecular mobility, measured as enthalpy relaxation (ER) of amorphous irbesartan (IBS) in ASDs. |
Year of Publication | :
2018
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Journal | :
Pharmaceutical research
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Volume | :
35
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Issue | :
2
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Number of Pages | :
29
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Date Published | :
2018
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ISSN Number | :
0724-8741
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URL | :
https://dx.doi.org/10.1007/s11095-017-2296-y
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DOI | :
10.1007/s11095-017-2296-y
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Short Title | :
Pharm Res
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