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Impact of Drug-Polymer Miscibility on Enthalpy Relaxation of Irbesartan Amorphous Solid Dispersions.

Author
Abstract
:

Drug-polymer miscibility has been proposed to play a critical role in physical stability of amorphous solid dispersions (ASDs). The purpose of the current work was to investigate the role of drug-polymer miscibility on molecular mobility, measured as enthalpy relaxation (ER) of amorphous irbesartan (IBS) in ASDs.

Year of Publication
:
2018
Journal
:
Pharmaceutical research
Volume
:
35
Issue
:
2
Number of Pages
:
29
Date Published
:
2018
ISSN Number
:
0724-8741
URL
:
https://dx.doi.org/10.1007/s11095-017-2296-y
DOI
:
10.1007/s11095-017-2296-y
Short Title
:
Pharm Res
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