A Phase 2 randomized, observer-blind, placebo-controlled, dose-ranging trial of aluminum-adjuvanted respiratory syncytial virus F particle vaccine formulations in healthy women of childbearing age.
| Author | |
|---|---|
| Abstract | :
Respiratory syncytial virus (RSV) causes significant morbidity and mortality in infants. We are developing an RSV fusion (F) protein nanoparticle vaccine for immunization of third trimester pregnant women to passively protect infants through transfer of RSV-specific maternal antibodies. The present trial was performed to assess the immunogenicity and safety of several formulations of RSV F vaccine in 1-dose or 2-dose schedules. |
| Year of Publication | :
2017
|
| Journal | :
Vaccine
|
| Volume | :
35
|
| Issue | :
30
|
| Number of Pages | :
3749-3759
|
| Date Published | :
2017
|
| ISSN Number | :
0264-410X
|
| URL | :
https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(17)30681-3
|
| DOI | :
10.1016/j.vaccine.2017.05.045
|
| Short Title | :
Vaccine
|
| Download citation |