Studies on the development of ¹⁶⁹Yb-brachytherapy seeds: New generation brachytherapy sources for the management of cancer.
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| Abstract | :
This paper describes development of (169)Yb-seeds by encapsulating 0.6-0.65 mm (ϕ) sized (169)Yb2O3 microspheres in titanium capsules. Microspheres synthesized by a sol-gel route were characterized by XRD, SEM/EDS and ICP-AES. Optimization of neutron irradiation was accomplished and (169)Yb-seeds up to 74 MBq of (169)Yb could be produced from natural Yb2O3 microspheres, which have the potential for use in prostate brachytherapy. A protocol to prepare (169)Yb-brachytherapy sources (2.96-3.7 TBq of (169)Yb) with the use of enriched targets was also formulated. |
| Year of Publication | :
2015
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| Journal | :
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
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| Volume | :
101
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| Number of Pages | :
75-82
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| ISSN Number | :
0969-8043
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| URL | :
https://linkinghub.elsevier.com/retrieve/pii/S0969-8043(15)00098-6
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| DOI | :
10.1016/j.apradiso.2015.03.020
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| Short Title | :
Appl Radiat Isot
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