Implication of DNA repair genes in prostate tumourigenesis in Indian males.
| Author | |
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| Abstract | :
Prostate cancer (CaP) is the fifth most common cancer among Indian men. Tumour protein p53 (TP53) gene increases the fidelity of DNA replication and homologous recombination by transcriptional transactivation of mismatch repair (MMR) genes. DNA repair thus has a potential role in molecular carcinogenesis of CaP. The aim of the present study was to identify mutations, and polymorphisms in TP53 gene and MMR protein expression in CaP in Indian male population. |
| Year of Publication | :
2012
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| Journal | :
The Indian journal of medical research
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| Volume | :
136
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| Issue | :
4
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| Number of Pages | :
622-32
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| ISSN Number | :
0971-5916
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| URL | :
http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2012;volume=136;issue=4;spage=622;epage=632;aulast=Bansal
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| Short Title | :
Indian J Med Res
|
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