Mcm10 proteolysis initiates before the onset of M-phase.
| Author | |
|---|---|
| Abstract | :
Mcm10 protein is essential for initiation and elongation phases of replication. Human cells proteolyze Mcm10 during mitosis, presumably to ensure a single round of replication. It has been proposed that anaphase promoting complex ubiquitinates Mcm10 in late M and early G1 phases. |
| Year of Publication | :
2010
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| Journal | :
BMC cell biology
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| Volume | :
11
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| Number of Pages | :
84
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| Date Published | :
2010
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| URL | :
https://bmccellbiol.biomedcentral.com/articles/10.1186/1471-2121-11-84
|
| DOI | :
10.1186/1471-2121-11-84
|
| Short Title | :
BMC Cell Biol
|
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