Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice.
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Abstract | :
Previous studies demonstrated that coplanar polychlorinated biphenyls (PCBs) promote proinflammatory gene expression in adipocytes. PCBs are highly lipophilic and accumulate in adipose tissue, a site of insulin resistance in persons with type 2 diabetes. |
Year of Publication | :
2013
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Journal | :
Environmental health perspectives
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Volume | :
121
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Issue | :
1
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Number of Pages | :
105-10
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ISSN Number | :
0091-6765
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URL | :
https://ehp.niehs.nih.gov/doi/10.1289/ehp.1205421?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
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DOI | :
10.1289/ehp.1205421
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Short Title | :
Environ Health Perspect
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