Amyloid β-peptide (1-42)-induced oxidative stress in Alzheimer disease: importance in disease pathogenesis and progression.
| Author | |
|---|---|
| Abstract | :
Alzheimer disease (AD) is an age-related neurodegenerative disease. AD is characterized by progressive cognitive impairment. One of the main histopathological hallmarks of AD brain is the presence of senile plaques (SPs) and another is elevated oxidative stress. The main component of SPs is amyloid beta-peptide (Aβ) that is derived from the proteolytic cleavage of amyloid precursor protein. |
| Year of Publication | :
2013
|
| Journal | :
Antioxidants & redox signaling
|
| Volume | :
19
|
| Issue | :
8
|
| Number of Pages | :
823-35
|
| Date Published | :
2013
|
| ISSN Number | :
1523-0864
|
| URL | :
https://www.liebertpub.com/doi/10.1089/ars.2012.5027?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
|
| DOI | :
10.1089/ars.2012.5027
|
| Short Title | :
Antioxid Redox Signal
|
| Download citation |