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The Collaborative Cross, a community resource for the genetic analysis of complex traits.

Author
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Abstract
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The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.

Year of Publication
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2004
Journal
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Nature genetics
Volume
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36
Issue
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11
Number of Pages
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1133-7
ISSN Number
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1061-4036
URL
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https://doi.org/10.1038/ng1104-1133
DOI
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10.1038/ng1104-1133
Short Title
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Nat Genet
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