Predicting eating disorder and anxiety symptoms using disorder-specific and transdiagnostic polygenic scores for anorexia nervosa and obsessive-compulsive disorder.
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| Abstract | :
Clinical, epidemiological, and genetic findings support an overlap between eating disorders, obsessive-compulsive disorder (OCD), and anxiety symptoms. However, little research has examined the role of genetics in the expression of underlying phenotypes. We investigated whether the anorexia nervosa (AN), OCD, or AN/OCD transdiagnostic polygenic scores (PGS) predict eating disorder, OCD, and anxiety symptoms in a large developmental cohort in a sex-specific manner. |
| Year of Publication | :
2022
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| Journal | :
Psychological medicine
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| Number of Pages | :
1-15
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| Date Published | :
2022
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| ISSN Number | :
0033-2917
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| URL | :
https://www.cambridge.org/core/product/identifier/S0033291721005079/type/journal_article
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| DOI | :
10.1017/S0033291721005079
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| Short Title | :
Psychol Med
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