Research advances on the molecular mechanism of autophagy regulated by Porphyromonas gingivalis .
| Author | |
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| Abstract | :
Autophagy is an intracellular conservative degradation pathway. This event has been considered as a key step in host defense against bacterial infection. However, Porphyromonas gingivalis, as one of the evidence-sufficient periodontal pathogens, can utilize self-induced autophagy to achieve persistent intracellular survival and proliferation, which enable this organism to escape from host immune surveillance. This review focuses on molecular mechanism of P. gingivalis internalization and autophagy to illuminate its pathogenesis and to further explore the relationship between P. gingivalis and systemic diseases. |
| Year of Publication | :
2017
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| Journal | :
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
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| Volume | :
35
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| Issue | :
6
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| Number of Pages | :
654-658
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| Date Published | :
2017
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| ISSN Number | :
1000-1182
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| DOI | :
10.7518/hxkq.2017.06.017
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| Short Title | :
Hua Xi Kou Qiang Yi Xue Za Zhi
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