Neuron Astrocyte Signal Transduction
The long term goal of studies in my laboratory is to understand the role of lipid biomediators, in neuronal degeneration. Lipid biomediators include a wide range of compounds such as prostaglandins, leukotrienes, platelet activating factor lysophosphatidic acid (LPA), tumor necrosis factor and various cytokines. Currently, we are examining the role of LPA in signaling pathways associated with neuronal degeneration (apoptosis) as a model for Alzheimers disease and head trauma. We utilize primary neurons primary astrocytes, primary microglial cells and immortalized neuronally derived cultures cells (for gene transfer studies) as our model systems. These studies suggest that lipid biomediators, in particular LPA likely play a role in neuronal degeneration.
GENERAL MICROBIOLOGY Fall-2012 Syllabus.docx(19.67 KB)
2012-Fall-Chapter 1-308-complete.pdf(1.2 MB)
2012-Fall-chapt3-308-complete.pdf(722.15 KB
2012-Fall-chapter 2-308-complete.pdf(1.1 MB)
2012-Fall-chapt4-308-complete.pdf(3.69 MB
2012-Fall-Chapt5-modified-308-complete.pdf(1.76 MB)
2012-Fall-chapt6-308-complete.pdf(2.6 MB)
2012-Fall-chapt7-308-complete.pdf(3.36)
(2.93 MB)MBTest 1 BIO 308 Spring 2012.docx
2012-Fall-chapt8-308-complete.pdf(2.17 MB)
There will be a review in room BS 107 on Tuesday Oct 9 at 5pm
GENERAL MICROBIOLOGY Spring 2015 Syllabus.docx
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Examination 1 Fall 2014.docx
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Spring 2015 Chapter 1.ppt --with news
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Spring 2015-Chapter 16.ppt
Spring 2015-Chapter 17.ppt
Spring 2015-Chapter 18.ppt
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Exam 3 BIO 308 Spring 2014.docx PRACTICE EXAM
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Question 43D is out